The process of developing technological research is being carried out beyond organizational boundaries, especially organizations that make intensive use of knowledge, such as Biotechnology. Considerable progress has been made in recent years in reducing costs and increasing the ease of gene sequencing and, ultimately, in activating or editing genes. In this context, discussions have been gaining prominence around Industry 4.0, in which new business models and intelligent processes for Biotechnology are evidenced. However, the challenges regarding the training and education of professionals are discussed, emphasizing the importance of a multidisciplinary education, unlike the more traditional nature of education in the areas of biology and sciences. These challenges can be partially transposed by strengthening the partnerships of universities and research centers with companies, in order to materialize in common projects, the demands of industries and the possibilities of transforming research projects into final products available to society. This paper presents a study on the impact of Industry 4.0 technologies on Biotechnology, and also presents the prospect of future professions with the influence of Industry 4.0. The results show that technologies such as artificial intelligence, robotics and 3D printing are promising in the development and advancement of Biotechnology. New automated laboratories are under development. Also, regulatory issues require a great deal of study, and business models will need to be more efficient to generate the results needed for the development of new drugs, food, and research of new products related to health.
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