The present issue of International Journal of Advances in Medical Biotechnology (IJAMB) introduces a set of five papers elaborated by Prof. Antonio Carlos Massabni and students that have attended a graduate course nominated Seminars of Integration from the Postgraduate Program in Biotechnology of the University of Araraquara (UNIARA), Araraquara, Brazil. The authors have focused on the impact of Industry 4.0 technologies on Biotechnology as well as the chance for future professionals and the work relations in this context. In other papers, the importance of biotechnology in the development of vaccines, antibiotics, hormones and scaffolds for regenerative medicine are discussed. This issue is dedicated in honor of Prof. Massabni for his commitment with teaching, research and administrative duties.