Skip to main navigation menu Skip to main content Skip to site footer

Research Paper

Vol. 5 No. 1 (2022): March-September

Use of high energy milling and porosity insertion in the development of the Mg-Zn system aiming biomedical applications



The development of metal alloys with porosity controlled by powder metallurgy has shown to be suitable for obtaining biomaterials with the control of mechanical strength and modulus of elasticity, in addition to the possibility of controlling open porosity, which is essential for osseointegration. Magnesium alloys have shown encouraging results when used as tissue engineering scaffolds. Although a considerable number of studies encourage the use of magnesium alloys in bioactive implants for load-bearing in orthopedic applications, a great deal of research effort is still essential to assess in vivo, the long-term capability of such supports. Due to the excellent physical and mechanical properties of magnesium compared to other permanent (non-degradable) elements, porous magnesium alloys have become good candidates to develop biodegradable supports for bone treatments. Porous magnesium alloys could be used in applications where it would be interesting to use a biodegradable metallic material, while maintaining the requirements of mechanical strength, elastic modulus, corrosion resistance and adequate osseointegration. In this work, a new route of processing porous alloys of the MgZn system using high energy milling, via powder metallurgy, will be evaluated.


  1. CHEN, H.; ZHANG, E.; YANG, K. Microstructure, corrosion properties and bio-compatibility of calcium zinc phosphate coating on pure iron for biomedical application. Materials Science and Engineering C, v. 34, no. 1, p. 201–206, 2014. Available at : <>.
  2. GHOSH, P., MEZBAHUL-ISLAM, M., MEDRAJ, M. Critical assessment and thermodynamic modeling of Mg–Zn, Mg–Sn, Sn–Zn and Mg–Sn–Zn systems. Calphad , 36 , 28–43, 2012.
  3. PALACIOS, C. The role of nutrients in bone health, from A to Z. Critical Reviews in Food Science and Nutrition, v. 46, no. 8, p. 621–628, 2006.
  4. YAZDIMAMAGHANI, M. et al. porous magnesium-based scaffolds for tissue engineering . Materials Science and Engineering C, v. 71, p. 1253–1266, 2017. Available at: <>.
  5. GERMAN, RM. Power metallurgy science. 2nd. ed. Princeton: Metal Powder Industries Federation, 1994.
  6. RAZAVI, M., YAZDIMAMAGHANI, M. VASHAEE, D., TAYEBI, L. Development and degradation behavior of magnesium scaffolds coated with polycaprolactone for bone tissue engineering. Materials Letters, 132, 2014. doi: 10.1016/j.matlet.2014.06.036.
  7. ZHANG, X., LI X.W., LI, J.G., SUN, X.D. Preparation and mechanical property of a novel 3D porous magnesium scaffold for bone tissue engineering . Mather Sci Eng C Mater Biol App, 42:362-7, 2014. doi: 10.1016/j.msec.2014.05.044. Epub 2014 May 25. PMID: 25063129.


Download data is not yet available.